Research Proposal on optimization the quality of anticoagulant in patient with Atrial fibrillation

The research proposal should be: ABSTRACT – A brief summary ( around 50 words) of the research

to be undertaken. It should preferably be written in non-technical language such that a non-

specialist in the discipline will know what the proposal involves. SYNOPSIS OF LITERATURE – An

introduction/synthesis of the key ideas & references that lead to the statement of the

research question & objectives. (There is no specified maximum number of words, bear in mind

this is not a literature review, and this section should be the minimum necessary to place the

proposal in context) RESEARCH QUESTION/OBJECTIVES – State briefly & clearly the research

question being asked & the objectives of the research. METHODOLOGY – A description of how the

research will be undertaken. Sufficient detail of methods, and of sample size, source etc

should be given so that it is clear how the methodology addresses the research aims.DATA

COLLECTION AND ANALYSIS . The supervisor said about second( research proposal) uploaded form

“I think that this has more potential but I’d be careful about limiting yourself to warfarin.

The coming years, during which you’ll be completing your PhD, will see more use of the novel

oral anticoagulants so I think that these need to be a focus to ‘future-proof’ your research.

There will need to be education of patients about these new agents too, especially in relation

to adherence as they typically have shorter half-lives than warfarin so missed doses will

potentially have a much more significant impact on efficacy”. I’m also not sure about the

truth of your statements “most pharmacists are not able to effectively advice their patients

on issues associated with warfarin treatment”, and “Improved pharmacist education on warfarin

management is the only effective way to optimize the use of it to improve patients’ adherence

to their treatment regimen”. Is the problem that pharmacists don’t know enough about warfarin,

or is it that they simply don’t have adequate opportunities to educate patients on warfarin?

We’ve already done some work in the area of pharmacist home visits incorporating warfarin

education in any case – please see attached. What I’d suggested, as mentioned below, is

initially the development of a prospective database to evaluate patients’ diet, antithrombotic

knowledge, anticoagulation satisfaction and adherence. This database can then be used to

identify patient outcomes and subsequently what the actual nature of any problems are – is it

a lack of information provided by healthcare professionals, or is it that healthcare

professionals don’t have sufficient opportunities to follow patients up to repeat the

important messages, or is it other factors interfering with adherence? You can then plan lack

an intervention to address these actual real world problems.
-Use about 5 -10 references ( articles) and do not focus only on warfarin.