Subject: Medicine and Health
As part of a recently funded NHMRC grant, you are studying the function of a putative ‘obesity’ gene, Agouti-related protein gene (ARPG). You have determined that both the mRNA and protein expression of ARGP is restricted to the hypothalamus in the brain. How would investigate the role of AGRP using a mouse model? You will need to explain the steps involved in creating the mouse model in the laboratory.
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